THe duramaximizer ( a pressure type box) raises fuel psi making more power where as most other chips/boxes/tuners just add more injection timing and injector pulse. I have no experience with it but i beleive it has its limits to what it can add as the dmax has a hard enough time keeping fuel psi with big programs let alone ask for moer psi. I think it works well by its self but is a good add on to a mild tune also!!!
thats what i have ppe hot et2 and the boost controller and it is awsome,lots of power and i mean stock tranny ripping power...oh ya i just bought a ppe stage V tranny and with the 1057 sun coast converter for that truck,getting it put in next week......i do know of sevaral LBZ's runnin the ppe hot et 2 stacked with the duramaximizer but they are all runnin bigger fuel pumps,and dyno around 500+rwhp...i take it that you don't have any performance tunes on your truck yet so in that case i would recommend the ppe it is a great tuner for the duramax......good luck on your choice