Think of the larger tire as a torque arm or cheater bar. When you have a really tight bolt you go and grab a longer wrench, right? A larger diameter tire is a longer "wrench" and increases the forces acting on the steering and suspension components and accelerates wear. The weight of the larger tires contributes to suspension wear but probably doesn't affect the steering stuff as much - but some for sure. Offset wheels or spacers for over-size tires are probably the worst as they increase loads and actually introduce a moment onto the wheel bearings. ALL factory wheels - cars, trucks, chevy, ford, toyota, hyundai.... are made to center the load on the center of the wheel bearing. Offsetting them puts a torsional load on the bearings that those bearings were never designed to see. Heck, you don't even have to drive it to do damage to those bearings. Just the 7,500 lb truck sitting in your driveway is putting a torsional load on the wheel bearings that is not there with factory or centered wheels. The farther the offset, the worse the load becomes as torque is calculated as force x length of moment arm. The longer the arm (long wrench), the higher the torque exerted (with the force applied being equal). In this case, the force is the weight of the truck / 4. The forces only grow when you hit potholes or curbs, etc. Those offsets also place additional stress on components like ball joints, control arms, bushings and such.
Having said all that, it's not going to stop people from installing bigger tires. Heck, I run over-size tires on my truck. It came with 245/75 16s and I ran those for the first 207,000 miles. But eventually I got tired of looking at it with those little tires in those HUGE wheel wells so I bumped up the tire size to 265s. They look a lot better and I still didn't need to lift or go to offset wheels.